SEMAPHORIN 3A CAUSES IMMUNE SUPPRESSION BY INDUCING CYTOSKELETAL PARALYSIS IN TUMOUR-SPECIFIC CD8+ T CELLS


Effects of Open-Skill Exercises on Cognition on Community Dwelling Older Adults: Protocol of a Randomized Controlled Trial

(1) Cognitive function may benefit from physical exercise in older adults.However, controversy remains over which mode of exercise is more beneficial.(2) The aim of the proposed study is to investigate the effect of open-skill exercise training on cognitive function in community dwelling older adults compared with closed-skill exercise, cognitive t

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Back pain: diagnostic and differential aspects

Management of patients with back pain is an interdisciplinary problem requiring a package of diagnostic and differential measures.Despite the elaboration of algorithms Nibbles Tray for the differential diagnosis and therapy of back pain, a number of questions remain difficult to interpret, which can lead to diagnostic errors.This review considers t

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Alignment independent 3D-QSAR, quantum calculations and molecular docking of Mer specific tyrosine kinase inhibitors as anticancer drugs

Mer receptor tyrosine kinase is a promising novel cancer therapeutic target in Bronc Halter many human cancers, because abnormal activation of Mer has been implicated in survival signaling and chemoresistance.3D-QSAR analyses based on alignment independent descriptors were performed on a series of 81 Mer specific tyrosine kinase inhibitors.The frac

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